MATLAB

3D Subject-Specific Shape and Density Estimation of the Lumbar Spine from a Single Anteroposterior DXA Image Including Assessment of Cortical and Trabecular Bone

ABSTRACT:

Double Energy X-beam Absorptiometry (DXA) is the standard exam for osteoporosis conclusion and break hazard assessment at the spine. Be that as it may, various patients with bone delicacy are not analyzed thusly. Truth be told, standard investigation of DXA pictures does not separate among trabecular and cortical bone; neither particularly evaluate of the bone thickness in the vertebral body, which is the place the vast majority of the osteoporotic cracks happen. Quantitative Computed Tomography (QCT) is an elective system that defeats constraints of DXA-based conclusion. Be that as it may, because of the mind-boggling expense and radiation dosage, QCT isn’t utilized for osteoporosis administration.

We propose a technique that gives a 3D subject-particular shape and thickness estimation of the lumbar spine from a solitary anteroposterior (AP) DXA picture. A 3D factual shape and thickness show is fabricated, utilizing a preparing set of QCT filters, and enlisted onto the AP DXA picture with the goal that its projection matches it. Cortical and trabecular bone compartments are portioned utilizing a model-based calculation. Clinical estimations are performed at various bone compartments.

Precision was assessed by looking at DXA-inferred to QCT-determined 3D estimations for an approval set of 180 subjects. The shape precision was 1.51 mm at the aggregate vertebra and 0.66 mm at the vertebral body. Relationship coefficients among DXA and QCT-inferred estimations run from 0.81 to 0.97. The strategy proposed offers an wise 3D examination of the lumbar spine, which could possibly enhance osteoporosis and crack hazard appraisal in patients who had an AP DXA output of the lumbar spine without any extra examination.

BASE PAPER: 3D Subject-Specific Shape and Density Estimation of the Lumbar Spine from a Single Anteroposterior DXA Image Including Assessment of Cortical and Trabecular Bone

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